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Gordon CheneryMontgomery Bell Academy Freshman Biology (regular and honors), AP Biology, AP Environmental Science H.Charles Manning, Manning lab, Vanderbilt University Institute of Imaging Science The Manning lab is multi-disciplinary, having engineers, chemists, and molecular/cellular biologists working with imaging systems. They specialize in molecular imaging of cancer, and notably imaging-based assessment of response to anti-cancer pharmaceuticals in colorectal and breast cancer in mice and humans. They are a translational lab in that they work closely with attending physicians and surgeons. They are actively engaged in advancing novel methods to image molecular events that include receptor expression, proliferation, angiogenesis, and apoptosis. My specific research project involved testing a new drug against three colorectal cancer cell lines, and studying those cells responses to the drug by noting changes in their signal transduction pathways. By using the Western Blot procedure I was successful in determining their responses to the drug by changes in concentrations of both apoptotic and pro-survival proteins. During the next two years I will use my experience in teaching freshmen the basics of cells and cell signaling and survival and in teaching seniors cellular homeostasis and the correlation between signal transduction and cancer. |
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2008 Participants:
Front row:
Alison Douglas, Meghan Murphy, Stacy Klein-Gardner |
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